REAL-TIME INTERNET OF THINGS ARCHITECTURE FOR WIRELESS LIVESTOCK TRACKING


4-1BB Signaling in Conventional T Cells Drives IL-2 Production That Overcomes CD4+CD25+FoxP3+ T Regulatory Cell Suppression.

Costimulation with the recombinant SA-4-1BBL agonist of 4-1BB receptor on conventional CD4+ T cells (Tconvs) overcomes the suppression mediated by naturally occurring CD4+CD25+FoxP3+ T regulatory cells (Tregs).The mechanistic basis of this observation has remained largely unknown.Herein we show that Tconvs, but not here Tregs, are the direct target

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